A PARTIR DE OCTUBRE 2018
Se integrará en un proyecto puntero en pronóstico personalizado del cáncer.
Requisitos:
Título de Master
Nota media de Universidad superior a 8.
Contactar:
agandarillaslab@gmail.com
BIBLIOGRAFÍA ASOCIADA
>Gandarillas et al. Cell Death Differ.
Mammalian endoreplication emerges to reveal a potential developmental timer.
2018 Mar;25(3):471-476.
>Alonso-Lecue et al. Cell Death Dis.
Inefficient differentiation response to cell cycle stress leads to genomic instability and malignant progression of squamous carcinoma cells.
2017 Jun 29;8(6):e2901.
>Molinuevo R, Freije A, de Pedro I, Stoll SW, Elder JT, Gandarillas A. Oncogene.
FOXM1 allows human keratinocytes to bypass the oncogene-induced differentiation checkpoint in response to gain of MYC or loss of p53.
doi:10.1038/onc.2016.262
>Gandarillas et al, 2015. Molecular and Cellular Oncology.
The mitosis-differentiation checkpoint, another guardian of the epidermal genome.
Jan 21;2(3):e997127. doi: 10.1080/23723556.2014.997127.
http://www.tandfonline.com/doi/full/10.1080/23723556.2014.997127
>Freije et al, 2014. Cell Reports.Inactivation of p53 in Human Keratinocytes Leads to Squamous Differentiation and Shedding via Replication Stress and Mitotic Slippage.
2014 Nov 20; 9(4):1349-60. doi: 10.1016/j.celrep.2014.10.012.
http://www.cell.com/cell-reports/abstract/S2211-1247%2814%2900866-3