Friday 25 January 2013

EPIDERMAL STARS


We investigate the cell cycle and differentiation of skin epidermal cells. Both need to be coordinated as an orchestra to avoid neoplasic development.
In vitro, we study the links governing epidermal homeostasis that protect the skin from cancer.
Primary keratinocytes behave closely resembling the physiology of the skin.
In situ, we study skin cancer.
Our research walks on the edge between molecular developmental cues and human disease.

Primary human keratinocytes expresing a GFP form of a cell cycle regulator (GREEN) and a differentiation keratin (RED).
Skin from the Peadriatic Surgery Department of Valdecilla hospital in Santander.
Cell culture and staining by Laura Ceballos.